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Overall Health
Vitamin B2, also known as riboflavin, is one of the eight B vitamins and is a necessary component of two main coenzymes that assist in metabolism, cell respiration, and normal growth and development.

Gut Benefits
Riboflavin is obtained through diet and certain bacteria in the gut microbiome; some lactic-acid bacteria are known to produce low amounts of the vitamin. Conversely, supplementation of riboflavin can affect the gut microbiome itself by changing its composition, most notably by increasing the abundance of Faecalibacterium prausnitzii. Riboflavin supplementation is also important to prevent deficiencies that may lead to inflammation and tissue damage.

Overall Health
Vitamin B3, also known as niacin, is one of the eight B vitamins and an essential human nutrient. It is a precursor of coenzymes for dehydrogenases that are important to the catabolism of many foods, as well as being a part of cell signaling, DNA repair, and anabolism reactions for fatty acids and cholesterol.

Gut Benefits
Niacin is consumed as a part of a normal diet, as well as being produced by gut microflora. Supplementation with niacin has been shown to produce effects similarly to the effects of the SCFA (short chain fatty acid) butyrate by activating important colon receptors that help with cell anti-inflammatory and anticancer functions. Niacin supplementation has also been observed to attenuate the severity of colitis in this manner.

Overall Health
Vitamin C supports the immune system, the function of many enzymes, formation of collagen, acts as a messenger for neural pathways, and as an antioxidant.

Gut Benefits
Vitamin C improves the gut barrier, reduces inflammation in the gut and helps balance the good and bad bacteria.

Overall Health
Omega-3 fatty acids are polyunsaturated fatty acids essential to lipid metabolism and found in high concentrations in the brain. In general, supplementation with Omega-3 fats tends to lower risk for cancer, cardiovascular disease, cognitive decline, and contribute to improvements in mental health.

Gut Benefits
In relation to gut health, taking Omega-3 supplements has been seen impacting microbiota composition to a less dysbiotic condition and reducing inflammation. Other studies show the increase of probiotic bacteria like Bifidobacterium and support the recovery of gut health after treatments such as chemotherapy.