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Did you know you are genetically more microbe than human? Your microbiome consists of trillions of microbes, which outnumber the human cells in your body.
Not only that, no two microbiomes are the same. Even in identical twins, research shows that the gut microbiome varies and is considered as unique as the human fingerprint.
Understanding the diverse nature of the microbiome is the future of human health.
Floré is the world’s only 100% custom synbiotic (prebiotics + probiotics) in an easy to use once-a-day capsule made with 115+ qualified and clinically validated ingredients.
We utilize cutting-edge whole genome sequencing technology, and our patented bioinformatic pipeline to interpret the trillions of microbes in your gut and create formulations to meet your specific needs.
Scroll right to explore the history of the microbiome and Floré’s innovations in personalized wellness.
Carl Woese developed a method for sequencing 16S rRNA, which revolutionized microbiology by enabling the classification of microbes based on their genetics. This laid the groundwork for exploring the gut microbiome.
The first draft of the human genome was published by the International Human Genome Sequencing Consortium and Celera Genomics. Researchers hypothesized a link between gut microbes and disease, paving the way for genomic approaches.
Of the approximately 20,000 human genes discovered, 99.9% of human DNA between any 2 individuals is identical.
Advances in high-throughput sequencing enabled metagenomic studies, allowing scientists to sequence entire microbial communities without needing to culture individual species.
Initiated by the NIH, it aims to classify the microbial species in and on the human body. Whole Genome Sequencing of gut microbiota became a central component—mapping microbial diversity and functions.
Researchers began sequencing probiotic strains to better understand their functions and mechanisms. This helped identify genes involved in colonization, metabolic activity, and immune modulation.
With the advent of WGS, researchers began designing personalized probiotics and microbiome-based therapies. Clinical trials using microbiome-based treatments began.
Sun Genomics, the parent company of the Floré brand, was founded to develop precision probiotics to treat dysbiosis through the gut microflora and personalized solutions. Growing from its flagship product it now also includes Floré Clinical and a range of accessible products such as Defense, Balance, and Performance.
CRISPR technology applied to the gut microbiome, enables precise editing of microbial genomes. This opens new possibilities for engineering probiotics and treating gut-related diseases.
Shotgun metagenomics became widely used for sequencing and analyzing the entire gut microbiome. This method provides detailed insights into microbial composition, function, and interactions.
Our team joins forces with Dr. Adams at ASU to launch a study looking at the impact of the microbiome and probiotics on symptoms for those on the autism spectrum.
Precision synbiotics increase gut microbiome diversity and improve gastrointestinal symptoms in our pilot open-label study with ASU's Autism/Asperger's Research Program finds. [Paper link]
Building on the research from our study, we launched Neurodiverse formulas tailored to specific areas of support. More Fundamental formulas launched to help with common GI symptoms and all based on over 7 years of custom formulas and customer feedback on formula success.
We create probiotics and prebiotics to meet a range of symptoms, goals, and budgets based on our years of microbiome analyses and formulations.
IBD involves chronic gut inflammation, often linked to gut microbiome imbalances. Probiotics may help restore microbial balance, reducing inflammation and improving symptoms.
Gut microbiota directly affect Autism symptoms. Individuals with Autism often have gut dysbiosis and our Mood and Pathways probiotics improve gut wellness, supporting metabolism and behavior.
Gut microbiome imbalances can contribute to obesity. Probiotics may support weight management by improving metabolism, reducing inflammation, and restoring wellnessy microbial diversity.
Gut microbiota influence cardiovascular wellness. Probiotics may reduce harmful metabolites, improve cholesterol, and support heart wellness by promoting beneficial microbial functions.
We perform internal cohort analyses based on Whole Genome Sequencing (WGS) microbiome data, Health & Diet Intake Data, and Formulation Data to assess the efficacy of our personalized products for individuals and cohort populations.
Autism is prevalent in 1 out of 36 children in the United States. The efficacy of prebiotics and probiotics (synbiotics when combined) to improve symptoms associated with Autism. Here, we present a precision synbiotic supplementation study in 296 children and adults clinically diagnosed with Autism versus 123 age-matched neurotypical controls. Precision synbiotics modulated the gut microbiome and could improve Autism-related symptoms.
4.25.24
Irritable Bowel Syndrome (IBS) is a prevalent, complex, chronic condition affecting approximately 10% of the global population. It is characterized by symptoms such as abdominal pain, bloating, and altered bowel habits, significantly impacting patients' quality of life. A notable aspect of IBS is dysbiosis, characterized by reduced microbial diversity, a lack of beneficial bacteria, and an increase in pro-inflammatory bacteria.
11.2.21
Between 15% to 20% of adults and up to 33% of adults over the age of 60 years old are affected by chronic constipation. The frequency of bowel movements in constipation is fewer than 3 bowel movements per week. Symptoms include sensation of straining, lumpy or hard stools, feeling of incomplete evacuation, anorectal obstruction, or blockage, and may require manual maneuvers to facilitate bowel movement.
8.27.24
We can support you on the path to better wellness by providing you with the information you need to start the conversation, and we can provide tailored support for your provider.
