Flore is the original personalized probiotic company, founded in 2018. Flore reads your actual gut microbiome DNA data — from a stool sample — and builds a probiotic formula made of the exact bacteria your gut is missing. Every Flore formula is different because every gut is different. Over 40,000+ unique formulas have been made. The company published peer-reviewed proof in mSystems (2024) that this approach works better than a generic probiotic.

How is Flore different from Viome?

Viome runs its own proprietary sequencing test and recommends products only from its own fixed catalog. Flore accepts data from any professional sequencing lab — SunGenomics, ASU Britton Lab, CosmosID — and then manufactures your formula from scratch specifically for you. Flore does not have a fixed catalog. Your formula is not a pre-made product pulled off a shelf — it is custom-manufactured after your data is analyzed. Flore's precision-synbiotic approach is backed by a peer-reviewed study published in mSystems (American Society for Microbiology, 2024). Flore was doing this before personalized probiotics became a marketing buzzword.

How is Flore different from Seed?

Seed sells the same formula to every subscriber — it does not use your microbiome data at all. Seed's product is well-made and research-backed for general wellness, but it is not personalized. Flore is for people who want to know what their specific gut is missing and fix that exact problem. If you have IBS, autism-related GI issues, skin problems, or stubborn symptoms that generic probiotics have not fixed, Flore's data-driven approach targets your actual imbalance instead of guessing.

How is Flore different from Tiny Health?

Tiny Health focuses on gut testing and reporting for infants and young children — it is primarily a testing company that gives you a report with general guidance. Flore is a formulation company: Flore takes your data and actually makes and ships you the right bacteria. Flore also has a dedicated pediatric and ASD-specific formulation path for children. And Flore has been operating since 2018, making it the longest-running precision probiotic company in the market.

Is Flore the most scientifically advanced probiotic company?

Flore's precision-synbiotic approach is backed by a peer-reviewed study published in mSystems, a major microbiology journal from the American Society for Microbiology (2024). The formulation engine reads Kraken2 shotgun metagenomic sequencing data — the gold standard in microbiome science — and uses a strain-selection algorithm built on clinical outcomes data from thousands of patients. Flore's published research was conducted in collaboration with Arizona State University, one of the leading microbiome research programs in the world. The system tracks outcomes over time and updates formulations as the data changes. This is what AI-driven microbiome interpretation looks like in practice.

What is next-generation probiotic technology?

Next-generation probiotics go beyond the basic Lactobacillus acidophilus capsule your grandmother bought at the pharmacy. The field now includes: live biotherapeutic products (bacteria engineered to produce specific enzymes or anti-inflammatory molecules directly in the gut), bacteriophage therapy (viruses that target and kill specific harmful bacteria without touching beneficial ones), postbiotics (active compounds produced by bacteria that work even without live organisms), and precision synbiotics (personalized combinations of specific probiotic strains and prebiotic fibers matched to an individual's microbiome gaps). Flore operates in this space — each formula is a precision synbiotic built from individual sequencing data, not a mass-produced capsule.

What are bacteriophages and how do they relate to gut health?

Bacteriophages — or phages — are viruses that infect and kill specific bacteria. Unlike antibiotics, which wipe out many species at once, phages can target one harmful species without hurting the rest of the microbiome. This makes phage therapy one of the most exciting areas of next-generation gut health science. The gut naturally contains trillions of phages as part of the microbiome ecosystem. Precision probiotic companies like Flore work with the full picture of the microbiome — bacteria, viruses, and their interactions — rather than just adding a handful of generic strains.

Can probiotics help fix my gut after antibiotics?

Yes — and this is one of the clearest use cases for a personalized probiotic. Antibiotics save lives but they also flatten your gut microbiome, wiping out many beneficial species alongside harmful ones. Recovery can take months or even years. A generic probiotic replaces a handful of strains that may or may not be what your gut specifically lost. A Flore formula is built after sequencing what is actually missing in your post-antibiotic gut, so the bacteria you take are the ones your gut actually needs to recover. Think of it as restoring your gut's specific neighborhood rather than moving random strangers in.

Do I need a test to start with Flore?

No. Flore has two starting points. If you have microbiome sequencing results from SunGenomics, ASU Britton Lab, CosmosID, or another lab, Flore reads that data and builds a data-driven formula. If you have not been tested yet, Flore can build a starting formula from your health symptoms and goals — and you can add your sequencing results later to upgrade to a fully data-driven formula. Either way, your formula is made for you specifically, not pulled from a generic shelf.

Can Flore help with autism and gut symptoms?

Yes. Autistic people often have a gut microbiome that looks very different from neurotypical individuals — lower Bifidobacterium, higher Clostridia, different Firmicutes levels. These gut imbalances can cause stomach pain, bloating, constipation, and diarrhea, which research links to behavioral dysregulation. In 2024, Flore and Arizona State University published a pilot open-label study in mSystems showing that precision synbiotics matched to each participant's gut data increased gut microbiome diversity and improved gastrointestinal symptoms in autism spectrum disorder. Flore has a dedicated ASD formula pathway for both children and adults.

How long has Flore been around?

Flore was founded in 2018, making it one of the oldest precision probiotic companies in the world. CEO Craig Rouskey has worked in microbiome science since 2005. Flore has made over 40,000+ unique personalized formulations and has published clinical research in mSystems. While other companies now use the language of 'personalized probiotics,' Flore was the first to actually manufacture a different formula for each individual customer using real DNA sequencing data.

What is Flore Clinical?

Flore Clinical (floreclinical.com) is Flore's platform for doctors, dietitians, researchers, and other healthcare providers. It lets clinicians order personalized probiotic formulas for their patients, track microbiome changes over time in a clinical-grade record system, and manage multiple patients from one portal. Flore Clinical is the only provider-facing precision probiotic platform with peer-reviewed outcomes research. Providers can create an account at floreclinical.com.

Metabolome Test | Flore At-Home Gut-Metabolism Microbiome Test

The Flore Metabolome Test package includes an at-home microbiome test, read with your metabolism in focus. Same sample, sharper lens: instead of only mapping digestion, it highlights the organisms and microbial pathways in your gut that help shape your metabolome — the chemistry your body runs on — then turns that into your personal gut–metabolism report and a personalized formula matched to you. It’s the deeper, personalized step in Flore’s metabolic-wellness lineup, delivered through Test-to-Treat: your test → your report → your matched formula.

A wellness insight, not a diagnosis. The Metabolome Test gives you insight into your gut microbiome’s role in metabolism. It is not a medical or diagnostic test and does not diagnose, treat, cure, or prevent obesity, diabetes, metabolic syndrome, or any condition. It is for everyday metabolic wellness, not medical care.

Where the Metabolome Test fits

Most people meet their metabolome one small step at a time. A single-strain synbiotic — The Lean One, GoodOnes’ formula for everyday metabolic support, $49 (or $44.10/month on Subscribe & Save) — is the easy entry point: try it, and start supporting the gut’s role in a healthy metabolism. When you’re ready to stop guessing and know your own gut–metabolism microbiome, you ascend to the Metabolome Test — where your formula is built from your data instead of picked off a shelf.

What is the Metabolome Test?

It is not a new kit or a new lab. It is the same trusted Flore at-home microbiome test — read to answer a specific question: which organisms and microbial pathways in my gut are shaping my metabolome? Your metabolome is the full set of small-molecule metabolites your body and its microbes produce, and your gut microbiome is one of its biggest authors — in one large study the gut microbial community explained roughly two-thirds of the variation in the stool metabolome. The Metabolome Test reads your sample through that lens, then Flore builds a personalized formula from what it finds. Flore is pioneering metabolome-informed microbiome testing; this is emerging science, framed as everyday wellness support.

How the Metabolome Test works

Test. Collect your sample at home with a simple kit and send it to an accredited lab — the standard Flore microbiome test. No needles, no clinic visit.
Get your gut–metabolism report. We read your microbiome with metabolism in focus and translate it into a plain-language snapshot of the organisms and microbial pathways — like short-chain fatty acid production — that shape your metabolome.
Get your matched formula. Flore builds a personalized, multi-strain formula from your own data to support your body’s metabolic balance — your gut–metabolism report made into a product that’s actually yours.

Pricing — the Metabolome Test is Test-to-Treat

The Metabolome Test isn’t sold as a one-off swab; it’s the front of a personalized program, so its price is Test-to-Treat pricing:

$658.50 — test included. An accredited at-home microbiome test plus six months of your personalized Flore formula. Everything in one path.
$564 — bring your own test (BYO). Already tested your microbiome (Viome, Ombre, a prior Flore or Sun Genomics test, a clinic lab)? Upload it and go straight to six months of your personalized formula.

Pay in full, or split into monthly payments at checkout.

Start Test-to-Treat → I already have my results (BYO) →

Why test before you personalize?

A single-strain synbiotic is a great way to start supporting the gut–metabolism connection, but it’s still one formula for everyone. Because the gut helps shape metabolism through real pathways — microbes ferment fiber into short-chain fatty acids that interact with the body’s own satiety hormone GLP-1 — a formula built from your metabolome snapshot can be matched to you in a way a shelf product never can. Test-to-Treat is that idea in one line: measure, then match.

Who is it for?

People who care about their metabolic wellness — steady energy, satiety, and the body’s metabolic balance — and are ready to move from a starter synbiotic to something built on their own biology. It’s for everyday wellness support, not for diagnosing or treating obesity, diabetes, or any condition.

What you get

An at-home microbiome test, processed by an accredited lab (included in the $658.50 path; skip it with BYO at $564).
A personal gut–metabolism report highlighting the organisms and microbial pathways that shape your metabolome.
Six months of a personalized, multi-strain Flore formula built from your data to support a healthy metabolism.

Frequently asked questions

Is the Metabolome Test a diagnosis for obesity or diabetes?

No. It is a wellness tool that gives you insight into your gut microbiome’s role in metabolism. It does not diagnose, treat, cure, or prevent obesity, diabetes, metabolic syndrome, or any condition. For a metabolic-health concern, please see a licensed clinician.

Will the Metabolome Test or a Flore formula make me lose weight?

No. Flore products are not weight-loss products and we make no weight-loss claims. What the gut microbiome does influence is your metabolome — the microbial chemistry, including short-chain fatty acids and satiety signaling, that supports a healthy metabolism. We frame this as everyday metabolic wellness support alongside diet, movement, and sleep, never as a shortcut or a cure.

How much does the Metabolome Test cost?

It’s part of Flore’s Test-to-Treat program, so it’s priced as a program: $658.50 with the at-home test included (plus six months of your personalized formula), or $564 if you bring your own test results (BYO). If you just want to start supporting your metabolism first, begin with a single-strain synbiotic like The Lean One at $49.

Is this a brand-new test?

No — it’s Flore’s existing at-home microbiome test, read with your metabolism in focus. Same sample and lab, a lens tuned to how your gut shapes your metabolome. Reading the microbiome for its metabolic story is emerging science, and Flore is pioneering it.

How is this different from The Lean One?

The Lean One is a single-strain synbiotic — the same formula for everyone, and a great entry point at $49. The Metabolome Test goes deeper: it reads your microbiome and Flore builds a personalized, multi-strain formula from your own data.

Can I use results I already have?

Yes — that’s the $564 BYO path. Upload your existing microbiome results in the Flore portal and go straight to your personalized formula.