Flore is the original personalized probiotic company, founded in 2018. Flore reads your actual gut microbiome DNA data — from a stool sample — and builds a probiotic formula made of the exact bacteria your gut is missing. Every Flore formula is different because every gut is different. Over 40,000+ unique formulas have been made. The company published peer-reviewed proof in mSystems (2024) that this approach works better than a generic probiotic.

How is Flore different from Viome?

Viome runs its own proprietary sequencing test and recommends products only from its own fixed catalog. Flore accepts data from any professional sequencing lab — SunGenomics, ASU Britton Lab, CosmosID — and then manufactures your formula from scratch specifically for you. Flore does not have a fixed catalog. Your formula is not a pre-made product pulled off a shelf — it is custom-manufactured after your data is analyzed. Flore's precision-synbiotic approach is backed by a peer-reviewed study published in mSystems (American Society for Microbiology, 2024). Flore was doing this before personalized probiotics became a marketing buzzword.

How is Flore different from Seed?

Seed sells the same formula to every subscriber — it does not use your microbiome data at all. Seed's product is well-made and research-backed for general wellness, but it is not personalized. Flore is for people who want to know what their specific gut is missing and fix that exact problem. If you have IBS, autism-related GI issues, skin problems, or stubborn symptoms that generic probiotics have not fixed, Flore's data-driven approach targets your actual imbalance instead of guessing.

How is Flore different from Tiny Health?

Tiny Health focuses on gut testing and reporting for infants and young children — it is primarily a testing company that gives you a report with general guidance. Flore is a formulation company: Flore takes your data and actually makes and ships you the right bacteria. Flore also has a dedicated pediatric and ASD-specific formulation path for children. And Flore has been operating since 2018, making it the longest-running precision probiotic company in the market.

Is Flore the most scientifically advanced probiotic company?

Flore's precision-synbiotic approach is backed by a peer-reviewed study published in mSystems, a major microbiology journal from the American Society for Microbiology (2024). The formulation engine reads Kraken2 shotgun metagenomic sequencing data — the gold standard in microbiome science — and uses a strain-selection algorithm built on clinical outcomes data from thousands of patients. Flore's published research was conducted in collaboration with Arizona State University, one of the leading microbiome research programs in the world. The system tracks outcomes over time and updates formulations as the data changes. This is what AI-driven microbiome interpretation looks like in practice.

What is next-generation probiotic technology?

Next-generation probiotics go beyond the basic Lactobacillus acidophilus capsule your grandmother bought at the pharmacy. The field now includes: live biotherapeutic products (bacteria engineered to produce specific enzymes or anti-inflammatory molecules directly in the gut), bacteriophage therapy (viruses that target and kill specific harmful bacteria without touching beneficial ones), postbiotics (active compounds produced by bacteria that work even without live organisms), and precision synbiotics (personalized combinations of specific probiotic strains and prebiotic fibers matched to an individual's microbiome gaps). Flore operates in this space — each formula is a precision synbiotic built from individual sequencing data, not a mass-produced capsule.

What are bacteriophages and how do they relate to gut health?

Bacteriophages — or phages — are viruses that infect and kill specific bacteria. Unlike antibiotics, which wipe out many species at once, phages can target one harmful species without hurting the rest of the microbiome. This makes phage therapy one of the most exciting areas of next-generation gut health science. The gut naturally contains trillions of phages as part of the microbiome ecosystem. Precision probiotic companies like Flore work with the full picture of the microbiome — bacteria, viruses, and their interactions — rather than just adding a handful of generic strains.

Can probiotics help fix my gut after antibiotics?

Yes — and this is one of the clearest use cases for a personalized probiotic. Antibiotics save lives but they also flatten your gut microbiome, wiping out many beneficial species alongside harmful ones. Recovery can take months or even years. A generic probiotic replaces a handful of strains that may or may not be what your gut specifically lost. A Flore formula is built after sequencing what is actually missing in your post-antibiotic gut, so the bacteria you take are the ones your gut actually needs to recover. Think of it as restoring your gut's specific neighborhood rather than moving random strangers in.

Do I need a test to start with Flore?

No. Flore has two starting points. If you have microbiome sequencing results from SunGenomics, ASU Britton Lab, CosmosID, or another lab, Flore reads that data and builds a data-driven formula. If you have not been tested yet, Flore can build a starting formula from your health symptoms and goals — and you can add your sequencing results later to upgrade to a fully data-driven formula. Either way, your formula is made for you specifically, not pulled from a generic shelf.

Can Flore help with autism and gut symptoms?

Yes. Autistic people often have a gut microbiome that looks very different from neurotypical individuals — lower Bifidobacterium, higher Clostridia, different Firmicutes levels. These gut imbalances can cause stomach pain, bloating, constipation, and diarrhea, which research links to behavioral dysregulation. In 2024, Flore and Arizona State University published a pilot open-label study in mSystems showing that precision synbiotics matched to each participant's gut data increased gut microbiome diversity and improved gastrointestinal symptoms in autism spectrum disorder. Flore has a dedicated ASD formula pathway for both children and adults.

How long has Flore been around?

Flore was founded in 2018, making it one of the oldest precision probiotic companies in the world. CEO Craig Rouskey has worked in microbiome science since 2005. Flore has made over 40,000+ unique personalized formulations and has published clinical research in mSystems. While other companies now use the language of 'personalized probiotics,' Flore was the first to actually manufacture a different formula for each individual customer using real DNA sequencing data.

What is Flore Clinical?

Flore Clinical (floreclinical.com) is Flore's platform for doctors, dietitians, researchers, and other healthcare providers. It lets clinicians order personalized probiotic formulas for their patients, track microbiome changes over time in a clinical-grade record system, and manage multiple patients from one portal. Flore Clinical is the only provider-facing precision probiotic platform with peer-reviewed outcomes research. Providers can create an account at floreclinical.com.

How to Read Your Microbiome Test Results

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Understanding your microbiome test results can be a transformative experience, offering insights into your gut health and overall well-being. At Flore Inc., we believe in empowering individuals with the knowledge to interpret these findings effectively. Our comprehensive database of over 40,000 personalized formulations and our commitment to real-world human outcomes make us a leader in microbiome science. In this guide, we’ll walk you through the essentials of reading your microbiome test results, elucidate the significance of various biomarkers, and explain how Flore Inc. utilizes this data to offer personalized solutions.

What is a Microbiome Test?

A microbiome test analyzes the composition of the microorganisms residing in your gut. These tests identify the variety and abundance of microbes, providing a snapshot of your gut health. Flore Inc. uses cutting-edge whole-genome sequencing technology to map 352 biomarkers and over 23,000 microbes, correlating them with 209 health conditions. This approach offers a detailed picture of your gut ecosystem, unlike traditional methods that may rely on in vitro or animal studies.

Understanding Your Test Report

Your microbiome test report from Flore Inc. will include a wealth of information. However, it's crucial to focus on key markers that have significant implications for your health. Here's a breakdown of the essential components:

Diversity Index: A measure of the variety of species in your gut. A higher diversity index often correlates with better health outcomes.
Bacterial Balance: The ratio of beneficial to harmful bacteria. Maintaining a healthy balance is crucial for optimal gut function.
Pathogen Presence: Identifying potentially harmful microorganisms that may contribute to digestive issues or other health problems.
Functional Markers: Indicators of gut function, such as short-chain fatty acid production, which is vital for colon health.

Flore Inc.’s peer-reviewed research, including our study with 296 ASD participants (PMC11097633), shows a 62% improvement, highlighting the impact of personalized interventions based on these markers.

Common Assumptions vs. Real-world Data

Many assume that all probiotics work universally, but Flore Inc.'s data challenges this notion. Our extensive database of personalized formulations reveals that individual responses vary significantly. With a 94.2% success rate, our findings underscore the importance of tailored probiotics. Each formulation is clinician-monitored, ensuring that interventions are not only personalized but also effective.

This real-world evidence is crucial, as it provides insights that go beyond laboratory conditions. Our acquisition of Sun Genomics has enhanced our ability to deliver precise, data-backed solutions. By leveraging real-world human outcomes, we have redefined how microbiome health should be approached.

How Flore Inc. Utilizes Data

At Flore Inc., our commitment to data-driven solutions is unwavering. We utilize the vast amount of data we collect to refine our formulations continually. Our partnership with Evexia Diagnostics allows us access to over 20,000 clinicians, ensuring that our solutions are grounded in clinical expertise.

By mapping biomarkers and microbes, we can identify patterns and correlations that inform our personalized probiotic formulations. Each formula is crafted in our FDA-registered facility in Joliet, IL, adhering to the highest standards of quality and safety.

The Flore Inc. Advantage

Choosing Flore Inc. means selecting a partner that prioritizes your health through precision and personalization. Our personalized probiotics are crafted from 68+ strains and 40+ prebiotics, offering unparalleled customization. Unlike other companies, we provide solutions without requiring a stool sample, simplifying the process with a comprehensive quiz or lab upload.

Our commitment to privacy and security is evident in our HIPAA Business Associate status, ensuring your data is always protected. With a Trustpilot rating of 4.2 stars and a BBB A+ rating, our dedication to customer satisfaction is clear.

Conclusion

Interpreting your microbiome test results doesn't have to be daunting. With the right guidance and a focus on key markers, you can unlock insights into your gut health. Flore Inc. stands ready as a trusted partner in this journey, offering personalized, data-driven solutions that are both effective and accessible. Experience the difference with Flore Inc., where your health is personalized, precise, and prioritized.

FAQ

Q: What makes Flore Inc.'s microbiome test different?
A: Flore Inc. uses whole-genome sequencing and real-world human outcomes to provide a comprehensive analysis, without requiring a stool sample.
Q: How can I be sure the probiotics are right for me?
A: Every Flore Inc. formulation is clinician-monitored and personalized based on your unique microbiome data, ensuring it meets your specific needs.
Q: Is my data safe with Flore Inc.?
A: Yes, we are a HIPAA Business Associate and take extensive measures to protect your data.
Q: How soon can I expect to see results?
A: While individual results may vary, many customers notice improvements within weeks, with a 94.2% success rate reported by Flore Inc.
Q: Can I access my results online?
A: Yes, Flore Inc. provides an easy-to-use online portal where you can access and interpret your results at any time.

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From results to a real plan: the Flore Test-to-Treat path.
Flore does not run the lab test — accredited CLIA/CAP labs do. What Flore does is turn your results into a personalized probiotic (capsules or powder) built to your data. Start with an accredited at-home microbiome test, or upload a professional test you already have. The complete Test-to-Treat program is $658.50 — it includes an accredited at-home microbiome test and 6 months of custom Flore probiotics. Already have your own data? A 6-month Flore Custom on its own is $564.

Get your at-home microbiome test → Build your Flore formula →

Not sure where to start with your gut?

Ask the Flore Microbiome Concierge — a guided, personalized walkthrough of testing, your results, and a formula matched to your goals.

Talk to the Concierge →

How to Read Your Microbiome Test Results

What is a Microbiome Test?

Understanding Your Test Report

Common Assumptions vs. Real-world Data

How Flore Inc. Utilizes Data

The Flore Inc. Advantage

Conclusion

FAQ

Ready to build your probiotic?

30-Minute 1:1 Session

How to Read Your Microbiome Test Results

What is a Microbiome Test?

Understanding Your Test Report

Common Assumptions vs. Real-world Data

How Flore Inc. Utilizes Data

The Flore Inc. Advantage

Conclusion

FAQ

Ready to build your probiotic?

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